CORADEGHINI , Rosella

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A great effort has recently been made to obtain human stem cells able to differentiate into cholinergic neurons, as a number of diseases are associated to the cholinergic neuron loss, degeneration or incorrect function (Alzheimer's disease and motor neuron disease). A stem cell population (i.e. pre-adipocytes) is present in the adipose stromal...

Stem cell models offer an opportunity both for therapeutic use and for the assessment of alternative in vitro models. Human lipoaspirate is a source of adult stem cells (pre-adipocytes), which are able to differentiate into various phenotypes, such as neurogenic lineage. Here, we analyse the suitability of these in vitro models in screening...

Abbiamo ottenuto neuroni post-mitotici e colinergici da pre-adipociti prelevati da operazioni di liposuzione

Environmental pollutants exhibit a variety of adverse biological effects on human health. Polychlorinated Biphenyls (PCBs) can modulate differentiation, metabolism and function of the white adipose tissue (WAT) in humans through a wide range of mechanisms able to exert their effects in the whole organism. Moreover, interactions among different...