COZZOLINO , Marco

Photoactivation is a physical process that allows using light-matter interaction as a precursor to induce a specific Physico-chemical reaction. This reaction is induced after the absorption of a photon, having a suitable wavelength, by specific photoactivable molecules. Such molecules act as a molecular machine that performs functions useful...

Hutchinson-Gilford Progeria Syndrome (HGPS) is a lethal congenital disorder characterized by premature aging symptom in children and early death. It is often used as model to understand the molecular mechanism of aging. This condition is caused by a single nucleotide substitution which leads a cryptic splice site in the C-terminal Lamin A....