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Last name: CABRIA
First name: Manlio
18F-NaF-PET/CT can detect mineral metabolism within atherosclerotic plaques. To ascertain whether their 18F-NaF uptake purports progression, this index was compared with subsequent morphologic evolution.
Background and Aims: 18F Natrium Fluoride (NaF) has been proposed as a clinical tool to identify and quantify ongoing arterial calcification. Estimation of NaF uptake by vessel walls is feasible in the majority of large vessels; it is conversely more challenging within the coronary tree, given the small size of these vessels and the artifacts...
Several studies have highlighted the role of vascular (18)F-NaF uptake as a marker of ongoing calcium deposition. However, accumulation of (18)F-NaF is often inconsistent with localization of arterial plaque. Calcification activity and thus (18)F-NaF uptake might prevail in the earlier plaque stages. To test this hypothesis, we evaluated...