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CAGNARD , Nicolas

Last name: CAGNARD

First name: Nicolas

October 2017 (v1)

Journal article

Metadata-only

Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas

Bal, Elodie Park, Hyun-Sook Belaid-Choucair, Zakia

Basal cell carcinoma (BCC), the most common human cancer, results from aberrant activation of the Hedgehog signaling pathway1. Although most cases of BCC are sporadic, some forms are inherited, such as Bazex–Dupré–Christol syndrome (BDCS)—a cancer-prone genodermatosis with an X-linked, dominant inheritance pattern2. We have identified mutations...

Uploaded on: August 24, 2024