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CAIZERGUES-FERRER , Michèle

Last name: CAIZERGUES-FERRER

First name: Michèle

August 8, 2016 (v1)

Publication

Metadata-only

Characterization of saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis

Rosado, Iván Dez, Christophe Lebaron, Simon

We report the characterization of the yeast Npa2p (Urb2p) protein, which is essential for 60S ribosomal subunit biogenesis. We identified this protein in a synthetic lethal screening with thersa3null allele. Rsa3p is a genetic partner of the putative RNA helicase Dbp6p. Mutation or depletion of Npa2p leads to a net deficit in 60S subunits and a...

Uploaded on: March 27, 2023