Objective Recent work has shown that people with common epilepsies have characteristic patterns of cortical thinning, and that these changes may be progressive over time. Leveraging a large multicenter cross-sectional cohort, we investigated whether regional morphometric changes occur in a sequential manner, and whether these changes in people...
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2022 (v1)PublicationUploaded on: February 14, 2024
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2022 (v1)PublicationTopographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy
Temporal lobe epilepsy, a common drug-resistant epilepsy in adults, is primarily a limbic network disorder associated with predominant unilateral hippocampal pathology. Structural MRI has provided an in vivo window into whole-brain grey matter structural alterations in temporal lobe epilepsy relative to controls, by either mapping (i) atypical...
Uploaded on: February 14, 2024