Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localised or generalised bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions,...
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2018 (v1)PublicationUploaded on: April 14, 2023
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2018 (v1)Publication
Pemphigus is a life threatening autoimmune epidermal blistering disease involving skin and mucous membranes. Pemphigus usually affects middle age men and women involving oral mucosa first and then spreading on the skin. It is caused by the presence of autoantibodies (IgG and less frequently by IgA) directed against desmogleins, and/or other...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Atopic dermatitis (AD) is a chronic inflammatory disease with increasing global incidence, which has a multifactorial pathogenesis and a variable expressivity. Clinical features of AD are different in adults compared to children, but it is well recognized the substantial impact of the disease on patients' quality of life at any age. Indeed,...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Introduction: Biologics have revolutionized the therapy of moderate-to-severe plaque psoriasis. Yet, despite their greater efficacy over conventional systemic therapies their high cost has represented a burden for healthcare systems, which limited their use. More recently, the availability of several biosimilars at low cost is changing the...
Uploaded on: April 14, 2023