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CAMELLO , Pedro J.

Last name: CAMELLO

First name: Pedro J.

September 26, 2022 (v1)

Publication

Metadata-only

Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells

Sánchez Collado, José López, José J. Jardín, Isaac

The identification of two variants of the canonical pore-forming subunit of the Ca2+ release-activated Ca2+ (CRAC) channel Orai1, Orai1α and Orai1β, in mammalian cells arises the question whether they exhibit different functional characteristics. Orai1α and Orai1β differ in the N-terminal 63 amino acids, exclusive of Orai1α, and show different...

Uploaded on: March 24, 2023