C

CAPONE M

Last name: CAPONE M

2014 (v1)

Publication

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IL-4-induced gene 1 maintains high Tob1 expression that contributes to TCR unresponsiveness in human T helper 17 cells

Santarlasci V Maggi L Mazzoni A

Human Th17 cells have a limited proliferative capacity compared to other T-cell subsets. We have shown that human Th17 cells display impaired IL-2 production due to IL-4- induced gene 1 (IL4I1) upregulation. Here, we show that in human Th17 cells, IL4I1 also maintains high levels of Tob1, a member of the Tob/BTG (B-cell traslocation...

Uploaded on: March 27, 2023
2012 (v1)

Publication

Metadata-only

Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

Santarlasci V Maggi L Capone M

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Uploaded on: March 27, 2023