INTRODUCCIÓN La Insuficiencia limbar (IL) es una enfermedad ocular debida a una disminución crítica de las células madre limbares encargadas de la renovación del epitelio corneal y de constituir una barrera entre el epitelio conjuntival, opaco, y el corneal, translúcido. Es conocida la relación entre el epitelio corneal y los nervios del plexo...
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April 8, 2016 (v1)PublicationUploaded on: December 4, 2022
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June 5, 2023 (v1)Publication
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Uploaded on: June 7, 2023 -
July 27, 2022 (v1)Publication
La COVID-19 (enfermedad por coronavirus 2019) nos plantea nuevos retos en nuestra rutina diaria. La última cifra publicada de sanitarios contagiados –se dejó de publicar por última vez el 18 de mayo– fue de 51,090 en total y 152 casos nuevos ese mismo día1. Por ello, debemos aprender a protegernos para continuar con nuestra rutina diaria...
Uploaded on: December 4, 2022 -
April 28, 2020 (v1)Publication
Purpose: In limbal stem cell deficiency, both the Ocular Surface Disease Index (OSDI) questionnaire and tear break-up time (BUT) are comparable between traditional methods and the Keratograph 5M. In this study, we aimed to correlate OSDI with Keratograph 5M interviewed OSDI, as well as slit-lamp tear BUT with Keratograph 5M noninvasive...
Uploaded on: December 4, 2022 -
November 14, 2022 (v1)Publication
Patients with severe limbal damage and limbal stem cell deficiency are a therapeutic challenge. We evaluated four decellularization protocols applied to the full-thickness and half-thickness porcine limbus, and we used two cell types to recellularize the decellularized limbi. The results demonstrated that all protocols achieved efficient...
Uploaded on: December 4, 2022 -
May 20, 2021 (v1)Publication
Purpose: Artificial tears only provide transient relief for dry eye. To the best of our knowledge, this is the first study to objectively compare treatment with artificial tears with Keratograph 5M, which allows accurate and objective investigation of dry eye and artificial tear treatment. We aimed to evaluate whether a preservative-free...
Uploaded on: March 25, 2023 -
February 1, 2024 (v1)Publication
Background/aims: Limbal stem cell deficiency (LSCD) is characterised by a marked decrease in limbal stem cells. It is classified primarily using subjective slit-lamp observations. In vivo confocal microscopy (IVCM) can non-invasively provide objective information on the condition of the limbal niche, the corneal epithelial basal cell density...
Uploaded on: February 4, 2024