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2022 (v1)PublicationUploaded on: July 3, 2024
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2021 (v1)Publication
Amyotrophic lateral sclerosis (ALS) is a fatal, multigenic, multifactorial, and nonācell autonomous neurodegenerative disease characterized by upper and lower motor neuron loss. Several genetic mutations lead to ALS development and many emerging gene mutations have been discovered in recent years. Over the decades since 1990, several animal...
Uploaded on: March 27, 2023 -
2018 (v1)Publication
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Uploaded on: April 14, 2023 -
2024 (v1)Publication
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Uploaded on: September 24, 2024 -
2019 (v1)Publication
Glutamate (Glu)-mediated excitotoxicity is a major cause of amyotrophic lateral sclerosis (ALS) and our previous work highlighted that abnormal Glu release may represent a leading mechanism for excessive synaptic Glu. We demonstrated that group I metabotropic Glu receptors (mGluR1, mGluR5) produced abnormal Glu release in SOD1G93A mouse spinal...
Uploaded on: April 14, 2023 -
2024 (v1)Publication
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Uploaded on: July 3, 2024 -
2024 (v1)Publication
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Uploaded on: October 15, 2024