En el siguiente trabajo, se presenta un modelo matemático que trata de simular una de las enfermedades óseas de mayor impacto a nivel mundial, la osteoporosis. Dicho modelo cuenta con gran variedad de parámetros de entrada y a través de las simulaciones realizadas, se trata de estudiar el efecto que producen en los parámetros de salida. Para...
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April 1, 2020 (v1)PublicationUploaded on: December 4, 2022
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November 27, 2017 (v1)Publication
La remodelación ósea es un mecanismo de auto-renovación natural del esqueleto de los seres vivos que involucra a un grupo de células que trabajan de manera coordinada: osteoblastos, osteoclastos, osteocitos y células de borde. Puede ser aleatoria, porque cada parte del esqueleto se renueva periódicamente o dirigida, como consecuencia de algún...
Uploaded on: March 27, 2023 -
April 20, 2023 (v1)Publication
Background and objectives: Blood vessels form a network of capillaries throughout the body that perform essential functions for life. Vasculogenesis, i.e. the formation of new blood vessels, is regulated by many factors, biochemical ones being among the most important. However, others such as the biomechanical influence on shape, organization...
Uploaded on: April 29, 2023 -
September 5, 2023 (v1)Publication
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel matrix, that are used, among other applications, as a technological platform to investigate tumor formation and evolution. Several interesting features can be replicated using this methodology, such as cell communication...
Uploaded on: October 18, 2023 -
June 26, 2023 (v1)Publication
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel matrix, that are used, among other applications, as a technological platform to investigate tumor formation and evolution. Several interesting features can be replicated using this methodology, such as cell communication...
Uploaded on: June 27, 2023