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CATANIA , Maria Vincenza

Last name: CATANIA

First name: Maria Vincenza

December 2011 (v1)

Journal article

Metadata-only

A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.

Davidovic, Laetitia Navratil, Vincent Bonaccorso, Carmela M

Fragile X syndrome (FXS) is the first cause of inherited intellectual disability, due to the silencing of the X-linked Fragile X Mental Retardation 1 gene encoding the RNA-binding protein FMRP. While extensive studies have focused on the cellular and molecular basis of FXS, neither human Fragile X patients nor the mouse model of FXS--the...

Uploaded on: December 4, 2022
March 2009 (v1)

Journal article

Metadata-only

FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure.

Bensaid, Mounia Melko, Mireille Bechara, Elias G

FRAXE is a form of mild to moderate mental retardation due to the silencing of the FMR2 gene. The cellular function of FMR2 protein is presently unknown. By analogy with its homologue AF4, FMR2 was supposed to have a role in transcriptional regulation, but robust evidences supporting this hypothesis are lacking. We observed that FMR2...

Uploaded on: December 3, 2022