CATENA , Silvia

Dendrimers are nanostructured "architectural motifs" with a well tailored polymeric structure, symmetric tree-like shape, the presence of several functional groups and inner cavities, and are of eminent interest in many biomedical applications as drug delivery, gene transfection and imaging. In this paper, reliable ...

Dendrimers are nanostructured "architectural motifs" which fascinate researchers fortheir several potentiality due to well‐tailored structure, symmetric tree‐like shape,and abilities in entrapping or binding hydrophilic or hydrophobic entities such asgenetic materials, drugs, and target molecules. Nowadays dendrimers inhabit thetop places among...

L-arginine is often used to decorate several scaffolds in order to obtain biomedical devices with increased efficiency and reduced toxicity, so nitrogen atoms need protection for example with BOC group. It has recently been reported that following three protocols which assured the achievement of the widely described...

It is well known that several polycyclic aromatic hydrocarbons (PAHs), products of incomplete pyrolysis of organic material, have proved to be extremely toxic to humans. Food can be contaminated by these compounds in many different ways and diet represents nowadays the major source of exposure to PAHs for non-smokers population. In the present...

Natural polyphenols such as Gallic Acid (GA) form an important class of bioactive chemical entities that, having innumerable biological properties, could represent a safer alternative to common drugs against several disorders, including platelet aggregation, radical oxygen species (ROS) hyperproduction, oxidative stress (OS) and bacterial...

Drugs delivered by proper carriers enter into the cells much more rapidly and carry out their action much more promptly than in the free forms. A high drug concentration can be sustained for longer periods of time at the target site in the cell. In in vivo conditions, this would translate into a reduction of systemic toxicity, dosage and...

It is well-known that the health properties attributed to several fruits, herbs, seeds and their processed foods/beverages are due to an important group of natural polyphenols classified as hydrolysable tannins (HT) named ellagitannins (ETs), that encompass both one or more gallic acid (GA) units and one or more hexahydroxydiphenoic acid (HHDP)...

Ellagic acid (EA) is a bioactive natural polyphenol with antioxidant and several other beneficial properties, but unfortunately it cannot be exploited for in vivo therapeutic applications because of its poor water solubility and accordingly low bioavailability. Aiming to increase EA solubility, an EA solid microdispersion was realized by...