In a phase-I-study recombinant interleukin-2 (rIL-2) in a dose from 0.01 to 0.3 mg/m2/day for 7 to 14 days was infused intraperitoneally. Side effects were fever and fluid retention. 2 patients showed a bacterial peritonitis after paracentesis. The investigations showed that the intraperitoneal (i.p.) administration of interleukin-2 activates...
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1989 (v1)PublicationUploaded on: March 31, 2023
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2011 (v1)Publication
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Uploaded on: April 14, 2023 -
2014 (v1)Publication
Background: Axillary lymph node dissection (ALND) in early-breast cancer patients with positive sentinel node (SLN+) may not always be necessary. Aims: To predict the finding of >= 1 metastatic axillary node in addition to SLN+(s); to discriminate between patients who would or not benefit from ALND. Methods: Records of 397 consecutive patients...
Uploaded on: April 14, 2023 -
1995 (v1)Publication
PURPOSE: The aim of this multicentric randomized trial was to determine whether reducing the interval between surgery and chemotherapy improves the outcome of breast cancer patients. PATIENTS AND METHODS: Between June 1985 and July 1992, 600 breast cancer patients, clinical stages T1-3A,N0-2,M0 were randomly assigned to a perioperative cycle...
Uploaded on: March 27, 2023