2008 (v1)
Publication
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Uploaded on: April 14, 2023
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2021 (v1)Publication
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Uploaded on: April 14, 2023 -
2022 (v1)Publication
Mechanisms for the generation of anti-dsDNA autoantibodies are still not completely elucidated. One theory states that dsDNA interacts for mimicry with antibodies raised versus other antigens but molecular features for mimicry are unknown. Here we show that, at physiological acid-base balance, anti-Annexin A1 binds IgG2 dsDNA in a competitive...
Uploaded on: February 14, 2024 -
2024 (v1)Publication
Deposition of autoantibodies in glomeruli is a key factor in the development of lupus nephritis (LN). For a long time, anti-dsDNA and anti-C1q antibodies were thought to be the main cause of the kidney damage. However, recent studies have shown that the list of autoantibidies that have renal tropism and deposit in the kidney in LN is increasing...
Uploaded on: July 13, 2024