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2022 (v1)PublicationUploaded on: January 31, 2024
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2022 (v1)Publication
Purpose: Inferior overall response rate with abemaciclib plus endocrine therapy was observed in patients with hormone receptor-positive/HER2-negative advanced breast cancer (BC) and BMI ≥ 25. We assessed the impact of baseline BMI on KI67% changes, achievement of complete cell cycle arrest (CCCA), clinical, and radiological responses in...
Uploaded on: March 27, 2023 -
2021 (v1)Publication
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Uploaded on: March 27, 2023 -
2022 (v1)Publication
Background: Surveillance of carbapenem-resistant Enterobacterales (CRE) carriers is the first measure of hospital infection control. Screening of CRE carriage can be assessed through culture and molecular techniques, each with specific properties of turnaroundtimes, sensitivity and specificity.Methods: This was a prospective study in a 1200-bed...
Uploaded on: January 31, 2024 -
2019 (v1)Publication
Background/Aim: A retrospective analysis of 388 patients with pure ductal carcinoma in situ (DCIS) was performed in order to test the correlation of clearance margin of resection and other host-, tumor- and treatment-related factors with ipsilateral breast tumor recurrence (IBTR). Materials and Methods: The pathological analysis was performed...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
BACKGROUND: The combination of cyclin-dependent kinases 4/6 inhibitors (CDK4/6is) and endocrine therapy (ET) is standard of care for patients with hormone receptor-positive (HR+), HER2-negative (HER2-) advanced breast cancer (BC). However, studies evaluating adjuvant CDK4/6is provided contradictory results thus far. MATERIALS AND METHODS: We...
Uploaded on: April 14, 2023 -
2021 (v1)Publication
Background: Immune checkpoint inhibitors (ICIs) have revolutionised clinical practice in oncology in the last years, leading to a survival benefit in several tumour types. To investigate whether these benefits are associated with improved quality of life, we conducted a systematic review and meta-analysis comparing patient-reported outcomes...
Uploaded on: April 14, 2023 -
2020 (v1)Publication
Background: The role of adjuvant chemotherapy in biliary tract cancer is controversial. We performed a systematic review and meta-analysis to assess the effect of adjuvant chemotherapy in biliary tract cancer patients. Methods: A literature search was performed to identify randomized controlled trials (RCTs) comparing adjuvant chemotherapy...
Uploaded on: April 14, 2023