C

M

CEREZO , Michael

Last name: CEREZO

First name: Michael

Email: Michael.CEREZO@univ-cotedazur.fr

Institution: UCA

Links

April 30, 2015 (v1)

Journal article

Metadata-only

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

Tichet, Mélanie Prod 'Homme, Virginie Fenouille, Nina

Disruption of the endothelial barrier by tumour-derived secreted factors is a critical step in cancer cell extravasation and metastasis. Here, by comparative proteomic analysis of melanoma secretomes, we identify the matricellular protein SPARC as a novel tumour-derived vascular permeability factor. SPARC deficiency abrogates tumour-initiated...

Uploaded on: February 28, 2023