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CESARINI , Valeriana

Last name: CESARINI

First name: Valeriana

September 21, 2021 (v1)

Publication

Metadata-only

ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

Jimeno González, Sonia Prados Carvajal, Rosario Fernández Ávila, María Jesús

The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA lesions. RNA editing, the post-transcriptional sequence alteration of RNA, has a profound effect on cell homeostasis, but its implication in the response to DNA damage was not previously explored. Here we show that, in response...

Uploaded on: December 4, 2022