C

CHAABANE L

Last name: CHAABANE L

2019 (v1)

Publication

Metadata-only

The danger signal extracellular ATP is involved in the immunomediated damage of α-sarcoglycan deficient muscular dystrophy

Gazzerro E Baratto S Assereto S

In muscular dystrophies, muscle membrane fragility results in a tissue-specific increase of danger-associated molecular pattern molecules (DAMPs) and infiltration of inflammatory cells. The DAMP extracellular ATP (eATP) released by dying myofibers steadily activates muscle and immune purinergic receptors exerting dual negative effects: a direct...

Uploaded on: April 14, 2023