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CHAHAL , Jasleen K

Last name: CHAHAL

First name: Jasleen K

January 2014 (v1)

Journal article

Metadata-only

R-spondin1 deficiency enhances β-Cell neogenesis in a murine model of diabetes.

Chahal, Jasleen K Wong, Victor S C Chaboissier, Marie-Christine

OBJECTIVE: The cWnt activator, R-spondin1 (Rspo1), regulates β-cell growth, function, and neogenesis, although its role in conditions such as streptozotocin (STZ)-induced diabetes is unknown. We hypothesized that Rspo1 deficiency enhances β-cell neogenesis in STZ-induced diabetes. METHODS: Wild-type (Rspo1) and knockout (Rspo1) mice were...

Uploaded on: October 11, 2023
January 2014 (v1)

Journal article

Metadata-only

R-spondin1 deficiency enhances β-Cell neogenesis in a murine model of diabetes.

Chahal, Jasleen K Wong, Victor S C Chaboissier, Marie-Christine

OBJECTIVE: The cWnt activator, R-spondin1 (Rspo1), regulates β-cell growth, function, and neogenesis, although its role in conditions such as streptozotocin (STZ)-induced diabetes is unknown. We hypothesized that Rspo1 deficiency enhances β-cell neogenesis in STZ-induced diabetes. METHODS: Wild-type (Rspo1) and knockout (Rspo1) mice were...

Uploaded on: December 3, 2022