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CHARD , Declan

Last name: CHARD

First name: Declan

2019 (v1)

Publication

Metadata-only

Default Mode Network Structural Integrity and Cerebellar Connectivity Predict Information Processing Speed Deficit in Multiple Sclerosis

Savini, Giovanni Pardini, Matteo Castellazzi, Gloria

Cognitive impairment affects about 50% of multiple sclerosis (MS) patients, but the mechanisms underlying this remain unclear. The default mode network (DMN) has been linked with cognition, but in MS its role is still poorly understood. Moreover, within an extended DMN network including the cerebellum (CBL-DMN), the contribution of...

Uploaded on: April 14, 2023
2017 (v1)

Publication

Metadata-only

The relationship between cortical lesions and periventricular NAWM abnormalities suggests a shared mechanism of injury in primary-progressive MS

Pardini, Matteo Petracca, Maria Harel, Asaff

In subjects with multiple sclerosis (MS), pathology is more frequent near the inner and outer surfaces of the brain. Here, we sought to explore if in subjects with primary progressive MS (PPMS) cortical lesion load is selectively associated with the severity of periventricular normal appearing white matter (NAWM) damage, as assessed with...

Uploaded on: April 14, 2023