C

J

CHERFILS-VICINI , J.

Last name: CHERFILS-VICINI

First name: J.

March 1, 2015 (v1)

Journal article

Metadata-only

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

Hofman, P. Cherfils-Vicini, J. Bazin, M.

Colitis-associated cancer (CAC) is a complication of inflammatory bowel disease (IBD). Binding of extracellular ATP to thepurinergic receptor P2RX7 has emerged as a critical event incontrolling intestinal inflammation, acting to limit elevation ofproinflammatory mast cells and cytokines and promote survival ofregulatory T cells (Treg) and...

Uploaded on: December 4, 2022