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CHERKASOVA , Vera

Last name: CHERKASOVA

First name: Vera

April 11, 2017 (v1)

Publication

Metadata-only

Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p

Cherkasova, Vera López Maury, Luis Bacikova, Dagmar

Deletion of the sla1+ gene, which encodes a homologue of the human RNA-binding protein La in Schizosaccharomyces pombe, causes irregularities in tRNA processing, with altered distribution of pre-tRNA intermediates. We show, using mRNA profiling, that cells lacking sla1+ have increased mRNAs from amino acid metabolism (AAM) genes and,...

Uploaded on: March 27, 2023