CHOVEAU , Frank

Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense research. We have previously identified a cytoplasmic domain, pCt, which plays a major role in...

Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense research. We have previously identified a cytoplasmic domain, pCt, which plays a major role in...

Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense research. We have previously identified a cytoplasmic domain, pCt, which plays a major role in...

Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense research. We have previously identified a cytoplasmic domain, pCt, which plays a major role in...

Inhibitory potassium channels of the TREK1/TRAAK family are integrators of multiple stimuli, including temperature, membrane stretch, polyunsaturated fatty acids and pH. How these signals affect the gating of these channels is the subject of intense research. We have previously identified a cytoplasmic domain, pCt, which plays a major role in...

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TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli,including bioactive lipids, mechanical stretch and temperature, into electrical signals.The nature of the structural changes that regulate their activity remains an openquestion. Here, we show that a cytoplasmic domain (the proximal C-ter domain, pCt)exerts...

TREK/TRAAK channels are polymodal K+ channels that convert very diverse stimuli,including bioactive lipids, mechanical stretch and temperature, into electrical signals.The nature of the structural changes that regulate their activity remains an openquestion. Here, we show that a cytoplasmic domain (the proximal C-ter domain, pCt)exerts...