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CHU , Y.

Last name: CHU

First name: Y.

January 12, 2023 (v1)

Publication

Metadata-only

Oral Administration of Tipranavir with Long-chain Triglyceride Results in Moderate Intestinal Lymph Targeting but no Efficient Delivery to HIV-1 Reservoir in Mesenteric Lymph Nodes

Chu, Y. Qin, C. Feng, W.

The introduction of combination antiretroviral therapy (cART) led to substantial improvement in mortality and morbidity of HIV-1 infection. However, the poor penetration of antiretroviral agents to HIV-1 reservoirs limit the ability of the antiretroviral agents to eliminate the virus. Mesenteric lymph nodes (MLNs) are one of the main HIV-1...

Uploaded on: March 24, 2023