CINOTTI , Raphaël

Introduction: Hyperglycemia is a marker of poor prognosis in severe brain injuries. There is currently little dataregarding the effects of intensive insulin therapy (IIT) on neurological recovery.Methods: A sub-group analysis of the randomized-controlled CGAO-REA study (NCT01002482) in surgical intensivecare units (ICU) of two university...

IntroductionHyperglycemia is a marker of poor prognosis in severe brain injuries. There is currently little data regarding the effects of intensive insulin therapy (IIT) on neurological recovery.MethodsA sub-group analysis of the randomized-controlled CGAO-REA study (NCT01002482) in surgical intensive care units (ICU) of two university...

Introduction Using a randomized controlled trial comparing tight glucose control with a computerized decision-support systems and conventional protocols (post hoc analysis), we tested the hypothesis that hypoglycemia is associated with a poor outcome, even when controlling for initial severity. Methods We looked for moderate (2.2-3.3mmol/l) and...