C

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CIULLO , Alessandra

Last name: CIULLO

First name: Alessandra

2019 (v1)

Publication

Metadata-only

Intravenous administration of cardiac progenitor cell-derived exosomes protects against doxorubicin/trastuzumab-induced cardiac toxicity

Milano, Giuseppina Biemmi, Vanessa Lazzarini, Edoardo

BACKGROUND: Combined administration of anthracyclines (e.g., doxorubicin; Dox) and trastuzumab (Trz), a humanized anti-human epidermal growth factor receptor 2 (HER2; ErbB2), is an effective treatment for HER2-positive breast cancer. However, both agents are associated with cardiac toxicity. Human cardiac-resident mesenchymal progenitor cells...

Uploaded on: April 14, 2023