C

J

CLAR , Julie

Last name: CLAR

First name: Julie

2015 (v1)

Journal article

Metadata-only

Hepatic lentiviral gene transfer prevents the long-term onset of hepatic tumours of glycogen storage disease type 1a in mice

Clar, Julie Mutel, Elodie Gri, Blandine

Glycogen storage disease type 1a (GSD1a) is a rare disease due to the deficiency in theglucose-6-phosphatase catalytic subunit (encoded by G6pc), which is essential forendogenous glucose production. Despite strict diet control to maintain blood glucose, patientswith GSD1a develop hepatomegaly, steatosis and then hepatocellular adenomas...

Uploaded on: February 28, 2023