2009 (v1)
Publication
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2011 (v1)PublicationEstrogens interfere with leflunomide modulation of cytokine production by human activated monocytes.
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2011 (v1)Publication
Studi recenti evidenziano che CTLA4-Ig svolge un'azione anti-infiammatoria agendo sia sull'interazione di diverse popolazioni cellulari (cellule presentanti l'antigene/cellule T) sia direttamente su singole cellule tra cui gli osteoclasti. In questo studio sono stati valutati gli effetti di CTLA4-Ig su singole colture di MS AR (in assenza di...
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2010 (v1)PublicationEstrogens interfere with leflunomide modulation of cytokine production by human activated monocytes.
Rheumatoid arthritis (RA) prevalence is greater in females than in males, supporting estrogens as modulators of immune response. Leflunomide (LEF) is employed in the RA treatment. We studied the combinatory effects of LEF active metabolite A77 1726 (LEF-M) and 17beta-estradiol (E2) on inflammatory cytokine production by cultured macrophages...
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1992 (v1)Publication
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1993 (v1)Publication
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Uploaded on: March 31, 2023 -
2009 (v1)Publication
Clinical and experimental evidence indicates that rheumatoid arthritis prevalence is greater in females than in males, and supports a role for estrogens as modulators of the immune response. Immunocytochemistry (ICC) showed that the antiproliferative drug Leflunomide (LEF) is successfully employed in rheumatoid arthritis. In this study we...
Uploaded on: April 14, 2023