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COJUTTI P.

Last name: COJUTTI P.

    Recent uploads

  • 2014 (v1)
    Publication
    Metadata-only
    Daptomycin underexposure in a young intravenous drug user who was affected by life-threatening Staphylococcus aureus-complicated skin and soft tissue infection associated with bacteraemia
    Pea F. Crapis M. Cojutti P.

    We describe the case of an intravenous drug user affected by life-threatening Staphylococcus aureus-complicated skin and soft tissue infection with associated bacteraemia who, while on replacement therapy with methadone, required 11 mg/kg/day daptomycin to achieve trough (Cmin) and peak (Cmax) plasma levels similar to those observed with the...

    Uploaded on: April 14, 2023
  • 2016 (v1)
    Publication
    Metadata-only
    Might isoniazid plasma exposure be a valuable predictor of drug-related hepatotoxicity risk among adult patients with TB?
    Cojutti P. Duranti S. Isola M.

    Objectives: To investigate the relationship between isoniazid plasma exposure and the likelihood of elevation of ALT (≥51 IU/L) among adult patients with TB. Methods: A retrospective observational study was conducted in patients who underwent periodic monitoring of hepatic function and in whom pharmacokinetic data were collected. Monte Carlo...

    Uploaded on: April 14, 2023
  • 2018 (v1)
    Publication
    Metadata-only
    Is meropenem MIC increase against KPC-producing Klebsiella pneumoniae correlated with increased resistance rates against other antimicrobials with Gram-negative activity?
    Cojutti P. Sartor A. Bassetti M.

    Objectives: The aim of this study was to assess the minimum inhibitory concentration (MIC) distribution for meropenem and other antimicrobials with Gram-negative activity against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) clinical isolates collected at a tertiary hospital in Italy between 2013–2016. Methods: The...

    Uploaded on: April 14, 2023
  • 2015 (v1)
    Publication
    Metadata-only
    Linezolid underexposure in a patient co-treated with venlafaxine
    Cojutti P. Crapis M. Bassetti M.

    No description

    Uploaded on: April 14, 2023
  • 2014 (v1)
    Publication
    Metadata-only
    Treatment of consecutive episodes of multidrug-resistant bacterial pleurisy with different aetiology in a heart transplant candidate: Proof of concept of pharmacokinetic/pharmacodynamic optimisation of antimicrobial therapy at the infection site
    Pea F. Cojutti P. Merelli M.

    No description

    Uploaded on: April 14, 2023
  • 2017 (v1)
    Publication
    Metadata-only
    Might real-time pharmacokinetic/pharmacodynamic optimisation of high-dose continuous-infusion meropenem improve clinical cure in infections caused by KPC-producing Klebsiella pneumoniae?
    Pea F. Della Siega P. Cojutti P.

    The effect of real-time pharmacokinetic/pharmacodynamic (PK/PD) optimisation of high-dose continuous-infusion meropenem on the clinical outcome of patients receiving combination antimicrobial therapy for treatment of KPC-producing Klebsiella pneumoniae (KPC-Kp) infections was retrospectively assessed. Data for all patients with KPC-Kp-related...

    Uploaded on: April 14, 2023
  • 2017 (v1)
    Publication
    Metadata-only
    Population pharmacokinetics of high-dose continuous-infusion meropenem and considerations for use in the treatment of infections due to KPC-producing Klebsiella pneumoniae
    Cojutti P. Sartor A. Righi E.

    We assessed the population pharmacokinetics of high-dose continuous-infusion (HDCI) meropenem in a cohort of patients with Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) infections. Monte Carlo simulations were used to define the permissible HDCI meropenem regimens that could be safely considered for the...

    Uploaded on: March 27, 2023
  • 2019 (v1)
    Publication
    Metadata-only
    Treatment of Candida infections with fluconazole in adult liver transplant recipients: Is TDM-guided dosing adaptation helpful?
    Righi E. Carnelutti A. Baccarani U.

    Background Fluconazole represents a common antifungal option for the treatment of Candida infections in liver transplant recipients. Although adequate antifungal exposure is known to correlate with favorable outcomes in patients with invasive candidiasis, therapeutic drug monitoring (TDM) of fluconazole is currently not recommended. Methods We...

    Uploaded on: April 14, 2023
  • 2014 (v1)
    Publication
    Metadata-only
    Intra-abdominal penetration and pharmacodynamic exposure to fluconazole in three liver transplant patients with deep-seated candidiasis
    Pea F. Righi E. Cojutti P.

    No description

    Uploaded on: April 14, 2023

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