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COLAROSSI , Cristina

Last name: COLAROSSI

First name: Cristina

2023 (v1)

Publication

Metadata-only

Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology

Ben Toumia, Iméne Bachetti, Tiziana Chekir-Ghedira, Leila

: Background and purpose: Lung cancer is the leading cause of death in both men and women, constituting a major public health problem worldwide. Non-small-cell lung cancer accounts for 85%-90% of all lung cancers. We propose a compound that successfully fights tumor growth in vivo by targeting the enzyme GARS1. Experimental approach: We present...

Uploaded on: February 13, 2024