COLOMBEL , Jean-Frédéric

Last name: COLOMBEL

First name: Jean-Frédéric

April 2, 2001 (v1)

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Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer

Desreumaux, Pierre Dubuquoy, Laurent Nutten, Sophie

The peroxisome proliferator–activated receptor γ (PPARγ) is highly expressed in the colon mucosa and its activation has been reported to protect against colitis. We studied the involvement of PPARγ and its heterodimeric partner, the retinoid X receptor (RXR) in intestinal inflammatory responses. PPARγ1/− and RXRα1/− mice both displayed a...

Uploaded on: May 28, 2023
2013 (v1)

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Functional Polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with Susceptibility to Inflammatory Bowel Diseases

Gensollen, Thomas Bourges, Christophe Rihet, Pascal

no abstract

Uploaded on: February 28, 2023
August 8, 2012 (v1)

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Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients with Refractory Crohn's Disease.

Desreumaux, Pierre Foussat, Arnaud Allez, Matthieu

BACKGROUND & AIMS: New therapeutic strategies are needed for patients with refractory Crohn's Disease (CD). We evaluated data from the Crohn's and T-regulatory Cell Study (CATS)1 to determine safety and efficacy of antigen-specific T regulatory (Treg) cells for treatment of refractory CD. METHODS: We performed a 12-week, open-labelled,...

Uploaded on: December 3, 2022

COLOMBEL , Jean-Frédéric

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