COMMOWICK , Olivier

The main objective of this thesis is to provide radio-oncology specialists with automatic tools for delineating organs at risk of a patient undergoing a radiotherapy treatment of cerebral or head and neck tumors.To achieve this goal, we use an anatomical atlas, i.e. a representative anatomy associated to a clinical image representing it. The...

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The registration of thoracic images is a challenging problem with essential clinical applications such as radiotherapy and diagnosis. In the context of the EMPIRE10 challenge, we brie y introduce a general robust and e cient algorithm to register automatically any type of scalar images (CT, MRI, ...) on virtually any location (brain, thorax,...

Conformalradiotherapyplanningneedsaccuratedelineations of the critical structures. Atlas-based segmentation has been shown to be very efficient to delineate brain structures. It would therefore be very interesting to develop an atlas for the head and neck region where 7 % of the cancers arise. However, the construction of an atlas in this...

Radiotherapy planning requires accurate delineations of the critical structures. To avoid manual contouring, atlas-based segmentation can be used to get automatic delineations. However, the results strongly depend on the chosen atlas, especially for the head and neck region where the anatomical variability is high. To address this problem,...

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The emergence of new modalities such as Diffusion Tensor Imaging (DTI) is of great interest for the characterization and the temporal study of Multiple Sclerosis (MS). DTI indeed gives information on water diffusion within tissues and could therefore reveal alterations in white matter fibers before being visible in conventional MRI. However,...

In this article, we focus on the parameterization of non-rigid geometrical deformations with a small number of flexible degrees of freedom. In previous work, we proposed a general framework called polyaffine to parameterize deformations with a finite number of rigid or affine components, while guaranteeing the invertibility of global...

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In this article, we focus on the computation of statistics of invertible geometrical deformations (i.e., diffeomorphisms), based on the generalization to this type of data of the notion of principal logarithm. Remarkably, this logarithm is a simple 3D vector field, and can be used for diffeomorphisms close enough to the identity. This allows to...

In this article, we focus on the parameterization of non-rigid geometrical deformations with a small number of flexible degrees of freedom . In previous work, we proposed a general framework called polyaffine to parameterize deformations with a finite number of rigid or affine components, while guaranteeing the invertibility of global...

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This document describes an implementation for GPU and CPU of Young and Van Vliet's recursive Gaussian smoothing as an external module for the Insight Toolkit ITK, version 4.* www.itk.org. In the absence of an OpenCL-capable platform, the code will run the CPU implementation as an alternative to the existing Deriche recursive Gaussian smoothing...

Warping a digital atlas toward a patient image allows the simultaneous segmentation of several structures. This may be of great interest for cerebral images, since the brain contains a large number of small but important structures (optical nerves, grey nuclei, etc.). One important application is the conformal radiotherapy of cerebral tumor,...

BACKGROUND AND PURPOSE: Conformal radiation therapy techniques require the delineation of volumes of interest, a time-consuming and operator-dependent task. In this work, we aimed to evaluate the potential interest of an atlas-based automatic segmentation software (ABAS) of brain organs at risk (OAR), when used under our clinical conditions....

Deforming a digital atlas towards a patient image allows the simultaneous segmentation of several structures. Such an intersubject registration is difficult as the deformations to recover are highly inhomogeneous. A priori information about the local amount of deformation to expect is precious, since it allows to optimally balance the quality...

Highly conformal irradiation techniques are associated with steep gradient doses. Accuracy and reproducibility of delineation are required to avoid geometric misses and to properly report dose-volume effects on organs at risk. Guidelines of the International Commission on Radiation Units have largely contributed to high quality treatments. The...

Intra-subject and inter-subject nonlinear registration based on dense transformations requires the setting of many parameters, mainly for regularization. This task is a major issue, as the global quality of the registration will depend on it. Setting these parameters is, however, very hard, and they may have to be tuned for each patient when...