C

J

CONTENTI , J.

Last name: CONTENTI

First name: J.

2023 (v1)

Journal article

Metadata-only

The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment

Contenti, J. Guo, Y Mazzu, A

Medulloblastoma is a cancerous brain tumor that affects mostly children. Among the four groups defined by molecular characteristics, Group 3, the least well characterized, is also the least favorable, with a survival rate of 50%. Current treatments, based on surgery, radiotherapy, and chemotherapy, are not adequate and the lack of understanding...

Uploaded on: January 13, 2025
November 30, 2023 (v1)

Journal article

Metadata-only

The mitochondrial NADH shuttle system is a targetable vulnerability for Group 3 medulloblastoma in a hypoxic microenvironment

Contenti, J. Guo, Y. Mazzu, A.

Abstract Medulloblastoma is a cancerous brain tumor that affects mostly children. Among the four groups defined by molecular characteristics, Group 3, the least well characterized, is also the least favorable, with a survival rate of 50%. Current treatments, based on surgery, radiotherapy, and chemotherapy, are not adequate and the lack of...

Uploaded on: January 13, 2025