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COPIN , Bruno

Last name: COPIN

First name: Bruno

2017 (v1)

Publication

Metadata-only

Contribution of LHX4 mutations to pituitary deficits in a cohort of 417 unrelated patients

Cohen, Enzo MAGHNIE, MOHAMAD Collot, Nathalie

CONTEXT: LHX4 encodes a LIM-homeodomain transcription factor that is implicated in early pituitary development. In humans, only 13 heterozygous LHX4 mutations have been associated with congenital hypopituitarism. OBJECTIVE: The aims of this study were to evaluate the prevalence of LHX4 mutations in patients with hypopituitarism, to define the...

Uploaded on: April 14, 2023