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CORCELLE-TERMEAU , Elisabeth

Last name: CORCELLE-TERMEAU

First name: Elisabeth

July 15, 2013 (v1)

Journal article

Metadata-only

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

Belaid, Amine Cerezo, Michaël Chargui, Abderrahman

Degradation of signaling proteins is one of the most powerful tumor-suppressive mechanisms by which a cell can control its own growth. Here, we identify RHOA as the molecular target by which autophagy maintains genomic stability. Specifically, inhibition of autophagosome degradation by the loss of the v-ATPase a3 (TCIRG1) subunit is sufficient...

Uploaded on: December 2, 2022
July 15, 2013 (v1)

Journal article

Metadata-only

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

Belaid, Amine Cerezo, Michaël Chargui, Abderrahman

Degradation of signaling proteins is one of the most powerful tumor-suppressive mechanisms by which a cell can control its own growth. Here, we identify RHOA as the molecular target by which autophagy maintains genomic stability. Specifically, inhibition of autophagosome degradation by the loss of the v-ATPase a3 (TCIRG1) subunit is sufficient...

Uploaded on: October 11, 2023