C

C

CORTI , Chiara

Last name: CORTI

First name: Chiara

2023 (v1)

Publication

Metadata-only

Tucatinib's journey from clinical development to clinical practice: New horizons for HER2-positive metastatic disease and promising prospects for brain metastatic spread

Criscitiello, Carmen Corti, Chiara De Laurentiis, Michelino

: Approximately 20% of breast cancers (BCs) overexpress human epidermal growth factor receptor 2 (HER2), a transmembrane glycoprotein with tyrosine kinase activity, encoded by ERBB2 gene. Historically, HER2 overexpression has been linked with increased disease recurrence and a worse prognosis. However, the increasing availability of different...

Uploaded on: February 4, 2024