COSCIA M.

Stroke often impairs the control of the contralesional arm, thus most survivors rely on the ipsilesional arm to perform daily living activities that require an efficient control of movements and forces. Whereas the ipsilesional arm is often called 'unaffected' or 'unimpaired', several studies suggested that during dynamic tasks its kinematics...

Multiple sclerosis is a complex neurological disease that results in motor impairment associated with muscle weakness and lack of motor coordination. Indeed, previous studies showed that, while activities in isolated arm muscles appeared generally similar to those of unimpaired subjects, shoulder muscle coordination with arm motions was...

This study investigated how stroke's hemispheric localization affects motor performance, spinal maps and muscle synergies while performing planar reaching with and without assistive or resistive forces. A lesion of the right hemisphere affected performance, reducing average speed and smoothness and augmenting lateral deviation in both arms....

The lesions induced by unilateral strokes perturb the complex and critical interhemispheric balance. While a high asymmetry measured in the acute phase is known to be a predictor for poor motor recovery, the evolution of this imbalance along motor recovery has not been studied. Here, we evaluated the evolution of the cortical power asymmetry...

Motor deficit is a prominent feature among stroke survivors. Robot-assisted therapies have been proposed as a strategy to boost rehabilitation, by allowing therapy to be provided in a more reproducible and intense manner, while quantitatively monitoring patient's improvement. However, those approaches have so far not shown superiority over...

Background: In the past years, robotic systems have become increasingly popular in upper limb rehabilitation. Nevertheless, clinical studies have so far not been able to confirm superior efficacy of robotic therapy over conventional methods. The personalization of robot-aided therapy according to the patients' individual motor deficits has been...

Stroke is a devastating neurological condition, often causing severe functional and cognitive deficits, sharply diminishing the patient's quality of life. Among others, robot-assisted rehabilitation has been widely proposed to enhance the rehabilitation outcome. However, clinical scores and robotic parameters often used to inform...

Objective. Several training programs have been developed in the past to restore motor functions after stroke. Their efficacy strongly relies on the possibility to assess individual levels of impairment and recovery rate. However, commonly used clinical scales rely mainly on subjective functional assessments and are not able to provide a...