Background: Real-world data (RWD) can contextualize clinical trial data. We present real-world evidence thatsupplemented the single-arm DESTINY-Breast01 trial, which assessed the efficacy and safety of trastuzumabderuxtecan (T-DXd) in patients with human epidermal growth factor receptor 2-positive (HER2þ) metastatic breastcancer (mBC)...
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June 3, 2024 (v1)Journal articleUploaded on: August 13, 2024
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May 2018 (v1)Journal article
BACKGROUND:For hormone receptor-positive (HR+) human epidermal growth factor receptor 2 (HER2-) negative metastatic breast cancer (MBC), international guidelines recommend endocrine therapy as first-line treatment, except in case of 'visceral crisis'. In the latter case, chemotherapy is preferred. Few studies have compared these two strategies....
Uploaded on: December 4, 2022