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COVEÑAS , Rafael

Last name: COVEÑAS

First name: Rafael

May 11, 2022 (v1)

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The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma

Muñoz Pinto, Mario Faustino Argüelles Castilla, Sandro Rosso, Marisa

Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately 15 months, despite the current aggressive treatment. Neurokinin-1 receptor (NK-1R) occurs naturally in human glioma, and it is necessary for the tumor development. Objective. The purpose of the study was to increase the...

Uploaded on: March 25, 2023
November 28, 2023 (v1)

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The substance P and neurokinin-1 receptor system in human thyroid cancer: An immunohistochemical study

Isorna Retamino, Inmaculada Esteban Ortega, Francisco Solanellas Soler, Juan

To develop a new therapeutic strategy against thyroid cancer (TC), the expression of both substance P (SP) and neurokinin-1 receptor (NK-1R) must be demonstrated in TC cells. This study aims to examine by immunohistochemistry the localization of SP and the NK-1R in human TC samples (papillary, follicular, medullary, anaplastic) in metastasis...

Uploaded on: November 30, 2023