CRESPAN , E.

Last name: CRESPAN

First name: E.

2013 (v1)

Publication

Metadata-only

Synthesis of pyrazolo[3,4-d]pyrimidines active on Bcr-Abl T315I mutation.

MUSUMECI, FRANCESCA BRULLO, CHIARA SCHENONE, SILVIA

No description

Uploaded on: April 14, 2023
2023 (v1)

Publication

Metadata-only

SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW 4-AMINO-PYRAZOLO[3,4-d]PYRIMIDINES AS POTENTIAL SRC KINASE INHIBITORS

Falesiedi, M. Cianciusi, A. Carbone, A.

The non-receptor tyrosine kinase (TK) Src plays a pivotal role in the signal transduction pathways involved in cell proliferation, survival, migration and angiogenesis. Src is implicated in different pathologies, including cancer, due to its strong proto-oncogenic activity, representing a key target for designing new therapeutic antitumor...

Uploaded on: February 13, 2024
2018 (v1)

Publication

Metadata-only

Pyrazolo[3,4-d]pyrimidines as tyrosine kinase inhibitors: synthesis and biological evaluation

Musumeci, F. Greco, C. Giacchello, I.

No description

Uploaded on: April 14, 2023
2011 (v1)

Publication

Metadata-only

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells

Radi, M. Brullo, C. Crespan, E.

Neuroblastoma (NB) represents the most common extracranial paediatric solid tumor for which no specific FDA-approved treatment is currently available. The tyrosine kinase c-Src has been reported to play an important role in the differentiation, cell-adhesion and survival of NB cells. Starting from dual Src/Abl inhibitors previously found...

Uploaded on: April 14, 2023
2018 (v1)

Publication

Metadata-only

Exploring SAR of a new generation of pyrazolo[3,4-d]pyrimidines as Fyn tyrosine kinase inhibitors

Musumeci, F. GRECO, CHIARA Navarro Pinin, L.

No description

Uploaded on: April 14, 2023

CRESPAN , E.

Recent uploads