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DÉRY , Marc-André

Last name: DÉRY

First name: Marc-André

September 2, 2005 (v1)

Journal article

Metadata-only

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.

Bilton, Rebecca Mazure, Nathalie Trottier, Eric

The hypoxia-inducible factor (HIF) is a key player in a transcriptional pathway that controls the hypoxic response of mammalian cells. Post-translational modification of the alpha subunit of HIF determines its half-life and activity. Among the multiple reported modifications, acetylation, by an acetyltransferase termed arrest-defective-1...

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