1996 (v1)
Publication
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Uploaded on: December 5, 2022
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2009 (v1)Publication
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1990 (v1)Publication
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2004 (v1)Publication
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2001 (v1)Publication
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2006 (v1)Publication
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2011 (v1)Publication
Glioblastoma (GBM) is the most common and aggressive neoplasia of the central nervous system in adults. Despite continued improvements in surgery, chemotherapy, and radiotherapy, clinical outcome is still dismal and better understanding of GBM biology is needed to develop novel therapies. Recent studies have demonstrated the existence of a...
Uploaded on: April 14, 2023 -
2006 (v1)Publication
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2008 (v1)Publication
Glioblastoma, the most aggressive cerebral tumor, is invariably lethal. Glioblastoma cells express several genes typical of normal neural stem cells. One of them, SOX2, is a master gene involved in sustaining self-renewal of several stem cells, in particular neural stem cells. To investigate its role in the aberrant growth of glioblastoma, we...
Uploaded on: May 13, 2023