1998 (v1)
Publication
No description
Uploaded on: December 2, 2022
D
Last name: DAPINO D
No description
No description
In Down's syndrome, the presence of three copies of chromosome 21 is associated with premature aging and progressive mental retardation sharing the pathological features of Alzheimer disease. Early cortical dysgenesis and late neuronal degeneration are probably caused by an overproduction of amyloid β-peptide, followed by an increased cellular...