2007 (v1)
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D
M
DELLA CHIESA , Mariella
Last name: DELLA CHIESA
First name: Mariella
Email: mariella.dellachiesa@unige.it
Institution: UNIGE
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2006 (v1)Publication
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2013 (v1)Publication
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2004 (v1)Publication
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2009 (v1)Publication
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2005 (v1)Publication
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2009 (v1)Publication
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2005 (v1)Publication
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2015 (v1)Publication
Natural killer (NK) cells are important players in the immune defense against viral infections. The contribution of activating killer immunoglobulin-like receptors (KIRs) and CD94/NKG2C in regulating anti-viral responses has recently emerged. Thus, in the hematopoietic stem cell transplantation setting, the presence of donor activating KIRs...
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2006 (v1)Publication
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2011 (v1)Publication
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2005 (v1)Publication
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2003 (v1)Publication
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2013 (v1)Publication
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2016 (v1)Publication
Human NK cells are distinguished into CD56brightCD16− cells and CD56dimCD16+ cells. These two subsets are conventionally associated with differential functional outcomes and are heterogeneous with respect to the expression of KIR and CD94/NKG2 heterodimers that represent the two major types of HLA-class I-specific receptors. Recent studies...
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2005 (v1)Publication
Natural killer (NK) cells were recently shown to play a relevant role in the process of dendritic cell (DC) maturation. This function is exerted either by direct DC stimulation or through killing those DCs that did not properly acquire a mature phenotype. While killing of immature DCs is dependent on the function of the NKp30 triggering...
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2005 (v1)Publication
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2017 (v1)Publication
Many evidences suggest that NK cells are effective in patrolling for and eliminating tumors in their onset phase, but hardly limit the progression of large established solid tumors. Beside the transition of tumor cells towards a more aggressive phenotype, the NK cell efficacy might be limited by a complex immunosuppressive milieu present in the...
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2012 (v1)Publication
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2005 (v1)Publication
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2005 (v1)Publication
In the course of inflammatory responses in peripheral tissues, NK cells may be exposed to cytokines such as IL-12 and IL-4 released by other cell types that may influence their functional activities. In the present study we comparatively analyzed purified human peripheral blood NK cells that had been exposed to either IL-12 or IL-4 during short...
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2011 (v1)Publication
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