DENTONE , Chiara

Background: Clinical Trials (CTs) are indispensable instruments for evidence-based medicine and frequently necessitate the management, sharing and analysis of large amounts of data amongst partners in different locations. Methods: To effectively satisfy these requirements, the proposed solution combines a web platform and a Clinical Data...

Abstract: Nel contesto sanitario, l'utilizzo dell'Information and Communication Technology (ICT) è diventato uno strumento fondamentale. A tale proposito, anche la Commissione Europea si è espressa in tale senso ("eHealth Action Plan 2012-2020 - Innovative healthcare for the 21st century", Brussels, 6.12.2012) evidenziando l'importanza...

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In the last century, antibiotics have been one of the most important discoveries for defeating numerous types of bacteria, but in recent times, microbes have become increasingly antibiotic resistant, causing severe consequences for human beings. The scientific community has been operating in this area for many years, developing projects always...

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Aims: Despite the remarkable efficacy shown in clinical practice, concerns have been raised about the costs associated with direct antiviral agent (DAA) therapy. This article presents the real-life costs for DAA treatment sustained by the Italian National Health Service in the Liguria Region (Northern Italy). Methods: A retrospective analysis...

Objectives: Chronic hepatitis C virus (HCV) is a leading cause of hospitalization and death in populations coinfected with human immunodeficiency virus (HIV). Sofosbuvir (SOF) is a pan-genotypic drug that should be combined with other agents as an oral treatment for HCV. We performed a 5-year horizon budget impact analysis of SOF-based regimens...

The problem of fighting antibiotic resistances, optimizing antibiotic usage and patients' care is one of the topics on which the scientific community is currently operating. For this purpose, the European Union has financed in 2012 a cross border project, involving Italy and France, focused on the design of a platform for the collection of data...

OBJECTIVES: Chronic HCV is a leading cause of hospitalization and death in populations coinfected with HIV in Italy. Sofosbuvir (SOF) is a pan-genotypic drug, which can be used alone or combined with other agents (e.g.Simeprevir,Daclatasvir, Ledipasvir) as oral treatment for HCV, with different price levels. We performed a 5 year-horizon budget...