D

DANOFF A

Last name: DANOFF A

2012 (v1)

Publication

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Alternative approach to insulin-like growth factor-1 inhibition for treatment of breast cancer.

AMERI, PIETRO Danoff A Kleinberg DL

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Uploaded on: April 14, 2023
2014 (v1)

Publication

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Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: a phase 1 proof of principle trial.

Singh B Smith JA Axelrod DM

IntroductionEstrogen inhibition is effective in preventing breast cancer in only up to 50% of women with precancerous lesions and many experience side effects that are poorly tolerated. As insulin-like growth factor I (IGF-I) underlies both estrogen and progesterone actions and has other direct effects on mammary development and carcinogenesis,...

Uploaded on: April 14, 2023