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DASURI , Kalavathi

Last name: DASURI

First name: Kalavathi

December 12, 2017 (v1)

Publication

Metadata-only

Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and tdp-43 regulation

Dasuri, Kalavathi Ebenezer, Philip J. Uranga, Romina M.

Amino acid analogs promote translational errors that result in aberrant protein synthesis, and have been used to understand the effects of protein misfolding in a variety of physiological and pathological settings. TDP-43 is a protein that is linked to protein aggregation and toxicity in a variety of neurodegenerative diseases. In this study we...

Uploaded on: March 27, 2023
April 16, 2021 (v1)

Publication

Metadata-only

Autophagic receptor p62 protects against glycation-derived toxicity and enhances viability

Aragonès, Gemma Dasuri, Kalavathi Olukorede, Opeoluwa

Diabetes and metabolic syndrome are associated with the typical American high glycemia diet and result in accumulation of high levels of advanced glycation end products (AGEs), particularly upon aging. AGEs form when sugars or their metabolites react with proteins. Associated with a myriad of age-related diseases, AGEs accumulate in many...

Uploaded on: March 27, 2023