D

G

DE OLIVEIRA , Gisele Pena

Last name: DE OLIVEIRA

First name: Gisele Pena

2016 (v1)

Publication

Metadata-only

Respiratory and systemic effects of LASSBio596 plus surfactant in experimental acute respiratory distress syndrome

Silva, Johnatas Dutra De Oliveira, Gisele Pena Samary, Cynthia Dos Santos

Background/Aims: Exogenous surfactant has been proposed as adjunctive therapy for acute respiratory distress syndrome (ARDS), but it is inactivated by different factors present in the alveolar space. We hypothesized that co-administration of LASSBio596, a molecule with significant anti-inflammatory properties, and exogenous surfactant could...

Uploaded on: April 14, 2023
2019 (v1)

Publication

Metadata-only

Glutamine therapy reduces inflammation and extracellular trap release in experimental acute respiratory distress syndrome of pulmonary origin

De Oliveira, Gisele Pena Kitoko, Jamil Zola De Souza Lima-Gomes, Phillipe

The innate immune response plays an important role in the pathophysiology of acute respiratory distress syndrome (ARDS). Glutamine (Gln) decreases lung inflammation in experimental ARDS, but its impact on the formation of extracellular traps (ETs) in the lung is unknown. In a mouse model of endotoxin-induced pulmonary ARDS, the effects of Gln...

Uploaded on: March 27, 2023